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The unclear mechanisms behind calcium's role in PXE relate to disrupted calcium metabolism, highlighting the necessity for comprehension to devise precise therapies and ongoing exploration of associated molecular and cellular pathways

GSH depletion and concomitant increase in O&NS and mitochondrial dysfunctions play a role in the pathophysiology of diverse neuroimmune disorders, including depression, myalgic encephalomyelitis/chronic fatigue syndrome and Parkinsons disease, suggesting that depleted GSH is an integral part of these diseases

Natural compounds as epigenetic regulators of CRC Ethnopharmacology involves studying how various cultures and indigenous peoples use natural substances for medicinal purposes

ROS includes: superoxide (O2 ), hydroxyl (OH), peroxyl (RO2 ), hydroperoxyl (HO2 ), alkoxyl (RO), peroxyl (ROO), nitric oxide (NO), nitrogen dioxide (NO2 ), and lipid peroxyl (LOO) and the non-radicals hydrogen peroxide (H2O2), hypochlorous acid (HOCl), ozone (O3), singlet oxygen (1g), and lipid peroxide (LOOH) [4]